Sample size calculation : Single group cohort

Epomedicine
August 13, 2020
Minimum sample size required can be calculated using the formula:
N=σ2(z1β+z1α/2)2(μ0μ1)2


μ0 = population mean

μ1 = mean of study population

N = sample size of study population

σ = variance of study population

α = probability of type I error (usually 0.05)

β = probability of type II error (usually 0.2)

z = critical Z value for a given α or β

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